Primers for Proteomics

This book contains examples written by internationally recognized experts applying proteomics and analysis applications of mass spectrometry in their everyday research. They dedicate this book to a broad audience of all scientists to encourage them to use the omics approach to investigate biological processes.

The first chapter is a short introduction to the basics of analytical chemistry. The following chapters describe high-throughput proteomic studies and how they are applied in various areas of biological and biomedical sciences, providing valuable insights into how biological systems work at the molecular level.

Contents:

• Analytical Primer (Katarzyna Pawlak and Pawel Ciborowski)
• Ionization The First Step of Mass Spectrometry-Based Proteomic Analysis (Katarzyna Macur)
• Basic Proteomics Protocols (Paulina Czaplewska and Marc Muller)
• Improving the Basic Workflow (Paulina Czaplewska, Natalia Musia, and Micha Puchalski)
• Amino Acid Sequence Databases and Search Engines Basic Tools in Proteomic/Peptidomic Research (Aleksandra E Bogucka and Stanisaw Odziej)
• Chemometrics in Proteomics (Beata Walczak)
• Basics of MS-Based Glycomic and Glycoproteomic Analysis of Glycoproteins (Yehia Mechref, Wenjing Peng, Cristian D Gutierrez Reyes, Andrew Bennett, Firas Kobeissy, and Stefania Mondello)
• Mapping Subcellular Proteomic Landscapes with Mass Spectrometry (Trisha Tucholski, Caleb Bridgwater, and Aleksandra Nita-Lazar)
• Cardiovascular Proteomics Primer: Managing Expectations and Setting Yourself up for Success (Linda Berg Luecke, Melinda Wojtkiewicz, Claudius Mahr, and Rebekah L Gundry)
• Amyloidosis
• Mass SpectrometryBased Immunopeptidomics for the Cancer Vaccine Science (Sachin Kote)
• Proteomics Approach to Viral Infections (Pawel Ciborowski and Michael Belshan)

Readership: Researchers and graduate students in Mass spectrometry and Proteomics.
Key Features:

• An easy read for beginners to be introduced to mass spectrometry based proteomics
• Provides an introduction to basic methodology of high-throughput data analysis and chemometrics
• Covers an application of proteomics in the study of complex biological systems

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