Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research.
Advanced Materials and Techniques for Biosensors and Bioanalytical Applicationsprovides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools.
Features:
Basic principles on different classes of biosensors, recent advances and applications
Smart materials for biosensors and other rapid, portable detection devices
Metal nanoparticles and nanocrystals for analytical applications
Carbon-based nanoparticles and quantum dots for sensing applications
Nanozymes as potential catalysts for sensing applications
Bioelectrochemiluminescence and photoelectrochemical-based biosensors
Paper electronics and paper-based biosensors
Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology
Biofuel cells as a signal transduction platform
FET-based biosensors, including ISFET and BioFET
This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.