Two psychopathic siblings, on the run with their irresponsible father from their demented mother, blend in with a parade of mass murderers weaving a trail of death and terror across the nation's highways.
Serial killers: They're everywhere! They're everywhere!
In this story, murderers and sadists of every type plague the U.S. highway system. But while those with the goriest nicknames earn the most media attention, none of them generates the kill numbers of an everyday-looking family a dad with his thirteen-year-old daughter and nine-year-old son - who leave mass bloodshed in their wake as they navigate Southwestern U.S. roadways with their dead cat in the trunk.
Hopefully, the cops are closing in on this peculiar clan of killers, but so are the kids' psychotic mom, as well as a caring aunt out to rescue the kids to a safe, caring home.
With murder and mayhem from start to finish, it's ... AMERICAN GENOCIDE!