Eric is finally getting free from the tumors (bodily and people-shaped), all that vermin, those Realtors, those Doctors, that tore his life apart. But as he'd be the first to tell you, if you cut out a tumor, you're left with a hole
But still, onwards; and Eric's steps aren't so unsteady anymore, and the puppy no the dog, is at his side.
"And the Puppy Ain't a Puppy No More" completes the story of getting back up and moving on after being hit by everything modern American life can throw.