American journalist Dana Pierson arrives in Tuscany expecting a week of great wine, sightseeing, and relaxation with her friend Father Giovanni Borelli. When millions of dollars' worth of Brunello di Montalcino is destroyed at the Borelli family vineyards, and the estate's elderly caretaker is found dead in a pool of wine, the two join forces for an adventure much different than planned.
From the lush backdrop of Tuscan vineyards and ancient villas, to the far reaches of Calabria, their search to learn who is responsible reveals deception, secrets, and family loyalties, as Dana realizes that people and wine are not always as they seem.