When his village is overrun by the undead, Jesse must flee into the wilderness armed only with his witsand an old M-16 assault rifle. After rescuing a woman who is about to give birth at any moment, he learns she is burdened with a secret that could change the world.
In a land overrun with zombies, bandits, militiamen, and hideous, fanged creatures called "smilers," the duo's greatest threat is the father of the woman's unborn child: a thinking, speaking zombie known as Doctor Vampire.