Epigenetics.The DNA of the pregnant mother

"Your maternal womb modifies the genetics of your baby conceived naturally or donated by another woman, as in a case of a lesbian couple (who'd prefer to use the ROPA method) or with an unrelated surrogate.
With healthy habits maintained over time we can optimise the inheritance we receive from our parents and grandmothers and pass it on to our grandchildren. "

I wrote "Epigenetics. The DNA of the pregnant mother" mainly thinking of all those women who assume that they must to give up all genetics to become a mother throught an egg/embryo donation, or thinking of doctors who don't remember that a woman is a unique human being, a life recipient and donor. AND GENETICS.

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1. INTRODUCTION
   What is Epigenetics?
   Beginning of epigenetic surveys: 3rd generation offspring of pregnant women in time of famine (World War II: Holland 1944/45)
   The influential environment

2.WILL MY GENES SHOW UP?
Genetic heritage is not always assured
Phenotype (physical traits)
Intelligence (high levels)
Diseases
Epimutations

3.DETRIMENTAL EPIGENETIC MEMORY
Cellular sensitivity to harmful environmental factors
A) During the embryonic stage
High stress or violent situations
Malnutrition of the mother
Exposure to tobacco during pregnancy
Intake of alcohol
B) During childhood and puberty
Missing figures for secure attachment
Emotional status of parents
Hereditary Poverty

4.GENES FOR HEALTH
From healthy genes to disease genes
Nutrition and maternal digestion
10 Daily routines that can reinterpret the DNA program of the embryo in the mother's womb
Physical contact
Healthy nutrition and intellectual performance
Positive experiences
Reduce fear or chronic stress
The game
Positive attitude
Moderate physical exercise
Secure attachment
Voice and language
Give and let them feed us
Reproductive health
A)Nutrients
Mineral Zinc and Vitamin B6
Omega 3 and 6 fatty acids
Vitamin C and E
Vitamin A
Selenium
B)Antinutrients
SugarAlcohol
Tobacco
Toxic metals
Birth control pill
Exposure to environmental chemicals
Homocysitein
Stress
Sexually transmitted diseases and bacterial infections

5.EPIGENETICS IN ASSISTED REPRODUCTION
At Square One: I am infertile
Active reception of fertilized eggs: not passive
The pregnant mother influence: Exchange between endometrium and the embryo
Is it possible to transmit physical features of the pregnant mother?
Graphic sequence of DNA modification by the pregnant mother
Similar? No coincidence!
The personality of the children is not determined by the donated eggs
Telling or keeping quiet in family
Anonymous Donor Vs. Known donor
Epigenetic footprint of in vitro treatments in embryos

6. ROPA METHOD (FERTILIZED EGG TRANSFER IN FEMALE COUPLES)
   ROPA Method: An Active Role in In Vitro Fertilization and Gestation for Both Women
   Maternal instincts in female couples
   Homoparental environment: Good gestational model
   7.CONCLUSIONS
   8.BIBLIOGRAPHY

Hope to hear from you soon.

By Sara Toledo.Madrid 2017

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