HIV-Associated Neurocognitive Disorders

pubblicato da Elsevier Science

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HIV-Associated Neurocognitive Disorders: Molecular and Cellular Mechanisms and Clinical Manifestations is a comprehensive volume on the field of HIV-Associated Neurocognitive Disorders (HAND) as well as its associated comorbidities. Covering clinical manifestations as well as molecular and cellular mechanisms, this book discusses available macaque and rodent animal models of HAND, epigenetic regulation, and signaling pathways underlying symptoms. Chapters also cover prevention and therapeutic strategies, as well as diagnosis and biomarkers associated with disease outcomes. This volume is appropriate for basic research and clinical investigators working in the area of HIV-1 infection.

Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities
Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms
Examines animal models for studying HAND, including macaque and rodent models
Presents insights into epigenetic regulation and signaling pathways implicated in HAND
Covers prevention, therapeutic strategies, and diagnostic approaches