Parkinson's disease is a chronic disorder characterized by progressive idiopathic parkinsonism is not associated with a widespread neurological involvement. Often the patient will realize later that you have family problems and even, initially, may not notice the presence of signs of disease at presentation because the symptoms can be very subtle and does not create significant disability to the patient. Also for this reason it is difficult for the physician to be able to go back to the start date of the disorders. Once the diagnosis of Parkinson's disease, the course of the disease is relentlessly progressive. However, in the course of different patients can be extremely variable, from cases in which there is a sudden progression of other disorders in which there are long periods of stability of the disease.