It is 1950s America and madness is in the air. In a world where the 'cures' for craziness include coma therapy, cyanide treatment and full-frontal lobotomies, Dr. William T. Friedrich, a young and ambitious psychology professor at Yale, stumbles upon a tropical plant that seems to possess the secret ingredient of happiness. In Casper Gedsic, a fiercely intelligent, socially inept, near-suicidal maths student, he seems to have found the perfect guinea pig. But when his experiments goes awry, Casper's thirst for revenge turns murderous and his actions have consequences that will haunt Friedrich and his family forever...