A clinical infectious diseases specialist based on the Island of Hawai'i, Dr. Jonathan Dworkin has served as an advisor to the mayors of Honolulu and Hawai'i counties during the COVID-19 crisis and has written widely about the state's faltering pandemic response. In Plague Doctors, his front-row seat and hands-on involvement provides invaluable insight into how the state handled-or mishandled-the first eighteen months of the pandemic. In an Afterword, Dworkin analyzes the current-day situation as of fall 2021 and the impacts of the delta variant.