Approach to the experimental pharmacology has been changed in past few years. It is due to the advancement in learning through computer based experimentations. Although it is effective, less expensive and save lives of thousands of experimental animals, understanding and implementation of such kind of knowledge for further study or in industries had certain limitations. Hence, there is a modify in the usual approach of gaining of knowledge, practical skills and developing attitudes in students. A need has, therefore, been felt for a manual that documents why and how a practical should be conducted. This book has fulfilled the need and, in fact, gone beyond merely fulfilling the need. The book has been written keeping in mind the preferred standard shift in the practical curriculum for undergraduate medical students. The chapters in the book have been prepared in sections like in-vivo pharmacology and Ex-vivo pharmacology mainly for clarity and convenience. The book covers all the possible exercises in pharmacology that can be carried out by most institutions, with minimal resources. A useful feature of this book is the sufficient use of diagram, which will help not only the trainee teachers but also the students to understand the mechanism. Each chapter is neatly presented with concision and precision. The objectives of learning are clearly defined, although they could well have been stated at the beginning of the chapter. The clear and relevant illustrations can substitute the lack of materials, which may be the case at some centers. The section on experimental pharmacology describes those experiments that are necessary for the student to understand the fundamental mechanisms of drug action. The author also emphasizes ethics in animal experimentation.