When it comes to unconditional love, Italian matriarch, Rose D'Orsi is deeply challenged. Nobody feels it more than Glory, her estranged 48-year-old lesbian daughter. Though Rose attracts the attention of Eli Fineman, a rich Bulgarian Holocaust survivor whose love, compassion, and wit affects people in unimaginable ways, he arrives too late in life to teach Rose how to be a good mother, even to Ricky, the child she favors. When Rose gets a terminal illness, Ricky is stretched beyond his limits, juggling a blue-collar job, a family, and his mothers unreasonable demands. Glory adds to the problem when she returns to Brooklyn to enlist her brother in a comically poignant effort to make peace with her abusive mother. Caught between two strong women, Ricky capitulates to his sister and theres hell to pay until Roses unfortunate death, which sets off a sequence of events that causes the siblings to question their life choices and each other. Sometimes it takes a personal tragedy to look within, but when Rose's will clouds everyone's judgment, it takes a bold act and a devastating catastrophe to elevate the human spirit.