Kent D. Luxe and a hairbrush named Sally Beaty are gathering dust on top of an old dresser. Down to his last dime, Kent's owner Bob tries to sell him, but no one wants a used comb. Instead, they separate during an eviction.
On an adventure, that takes Kent into the sewer, the ocean and finally the beach, a bite from The Mosquito Pire brings him to life. He saves a dying tube of lipstick from melting and then brings his friend Sally to life. Later, on a search for Bob, Kent and his friends discover a dark secret about his old landlord and they try to set things right.