Ex-pug and small-time hood, Mickey Walker, is down to nothing. Having gambled everything away and being faced with middle-age, Mickey feels as if he is left with only two options: to turn the .38 in his nightstand on himself or go back to work for Ned Kelly. Mickey chooses the latter and begins auctioning off his integrity to Ned Kelly, a low-level boss who runs a casino above the nickel and dime stores on Jamaica Avenue. The Last Round charts Mickey's descent into the multi-cultural underworld of Queens where he is forced to balance his loyalty to his brother and his desire for a normal life.