College student Anna Caldwell's life turns upside down after a traumatic car accident lands her in the hospital broken and battered with an ability to hear a voice inside her head. A series of unfortunate events leads Anna to learn she is part of a top-secret governmental organization, known as Department 126, whose last assignment led to her memories of being an agent erased. Upon attempting a procedure to regain her past identity, Anna comes face-to-face with 'the voice', initiating a two thousand year old rite of passage that pits Anna against varying factions whose strive for power places not only her life in peril, but the world's.