This issue of Hospital Medicine Clinics, edited by Dr. Eddy Chen, covers topics including: Being the Oncology Hospitalist; Caring for Acute Leukemics; Blood Transfusions for Cancer Patients; QI Initiatives in Hospitalized Cancer Patients; Febrile Neutropenia - A Closer Look; Chemotherapy Complications - Short and Long Term Issues; Malignant Bowel Obstruction; Tumor Lysis Syndrome; Principles of Radiation Therapy: What Hospitalists Need to Know; and Neoplastic Related Cord Compression.